This will be a short post because I don't know a lot of details yet. Honeywell is developing a new three part zeotropic refrigerant that can replace R410A. It has a relatively low GWP of 733 compared to 2088 for 410A, and most significantly, is non-flammable. Honeywell's trade name for it is Solstice N41, the ASHRAE number is R466A. It reportedly contains the same two chemicals as in R410A (R32 and R125). A third is added - trifluoroiodomethane (CF3I). This third component is currently used a a fire retardant. It also helps reduce the GWP of the mixture. The new refrigerant is not claimed to be a "drop-in" for R410A, but required design modifications are said to be minimal. The refrigerant is currently undergoing ASHRAE testing, but has received a preliminary A1 rating. I have now told you all I know, and it did not take very long. Here are links to two articles about this new refrigerant.
https://www.coolingpost.com/world-news/secret-of-honeywells-new-refrigerant/
https://www.coolingpost.com/world-news/honeywell-announces-r410a-breakthrough/
410a is considered to be more energy-efficient and eco-friendly, which may justify its higher cost in the long run. The 410a refrigerant price can vary depending on several factors such as location, supplier, and the quantity purchased.
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